Buy Aquazide tablets online from a USA pharmacy

| Product Name | Aquazide |
| Dosage | 12.5 mg, 25 mg, 50 mg |
| Active Ingredient | Hydrochlorothiazide |
| Form | Oral Tablets |
| Description | Thiazide diuretic used in the USA for hypertension and edema associated with heart failure, liver cirrhosis, and certain kidney disorders. |
| How to Order (Prescription Support) | U.S. Online Pharmacy with Telehealth Evaluation |
Aquazide is a brand of hydrochlorothiazide, a thiazide diuretic medicine that has been used for decades in the United States to help treat high blood pressure (hypertension) and fluid retention (edema). Lowering blood pressure reduces the risk of heart attack, stroke, kidney problems, and other cardiovascular complications. Hydrochlorothiazide tablets are commonly available in 12.5 mg, 25 mg, and 50 mg strengths in the U.S. market. The precise strength and dosing schedule should be selected by a licensed healthcare provider based on your health history, lab results, and blood pressure goals.
In the USA, Aquazide is a prescription medication. Many patients choose convenient online options that connect them with U.S.-licensed clinicians for a quick assessment, a legitimate prescription when appropriate, and home delivery from accredited pharmacies. This page provides evidence-based information about how hydrochlorothiazide works, who it’s for, safety considerations, dosing guidance, potential side effects and interactions, and practical tips for getting started.
Aquazide price and typical U.S. availability
Because hydrochlorothiazide has been available for many years, its generic versions are widely stocked in pharmacies across the United States and are typically low-cost. Prices vary by strength, quantity, and pharmacy discount programs. As a general orientation, 30 tablets of hydrochlorothiazide 12.5 mg or 25 mg often fall in a low-price tier at major retail chains, while 90-day supplies commonly provide the best per-tablet value. Branded Aquazide may cost more than generic hydrochlorothiazide, but many U.S. insurers and discount cards favor the generic option due to its comparable efficacy and safety profile.
Online pharmacies serving U.S. patients frequently offer transparent pricing and options to bundle an initial telehealth consultation with the medication. While exact prices change over time, it’s reasonable to expect competitive rates for 12.5 mg, 25 mg, and 50 mg strengths, with the lowest daily cost typically seen at 90-day quantities. Always compare shipping times, return policies, and the availability of pharmacist counseling when evaluating suppliers.
If you have insurance, your out-of-pocket price will depend on your plan’s formulary and copay tier. Without insurance, many pharmacies accept discount savings programs that can bring the cost of hydrochlorothiazide down significantly. Ask about generic pricing if Aquazide is not covered on your plan or carries a higher copay.
Where can I buy Aquazide in the USA?
In the United States, Aquazide (hydrochlorothiazide) is dispensed by prescription. Patients can obtain it at local brick-and-mortar pharmacies or via reputable U.S. online pharmacies. If you don’t yet have a prescription, select online services can connect you with a U.S.-licensed clinician for a brief telehealth evaluation. If appropriate, the clinician can issue a prescription that is sent to a partnered pharmacy for home delivery.
We collaborate with established pharmacy partners that prioritize medication authenticity, secure shipping, clear pricing, and continuous customer support. U.S. patients appreciate the convenience of doorstep delivery, automatic refills where permitted, and access to pharmacists who can answer questions about dosing, side effects, interactions, and refills.
Whether you prefer an in-person pharmacy pickup or a mail-order service, always verify that the pharmacy is licensed in your state. If you use an online service, look for published policies, a U.S. address and phone number, secure checkout, and access to pharmacist counseling. Avoid websites that offer “prescription” medications without any provider involvement or that ship from unknown sources.
Aquazide in the United States
Getting started with Aquazide is straightforward. After a clinician reviews your health history and, when relevant, your recent labs, you’ll receive dosing instructions customized to your needs. Most adults start with a once-daily dose, taken in the morning with water. Your provider may request periodic lab tests (electrolytes, kidney function) and blood pressure checks to ensure the medication is working safely and effectively.
What is Aquazide (hydrochlorothiazide)?
Hydrochlorothiazide belongs to a class of medicines called thiazide diuretics. These medications help your body eliminate excess salt (sodium) and water through urine by inhibiting sodium-chloride reabsorption in the distal convoluted tubule of the kidney. Over time, this diuretic effect helps reduce plasma volume and lowers peripheral vascular resistance, both of which contribute to lower blood pressure. Thiazides also reduce urinary calcium excretion, which is why hydrochlorothiazide is sometimes used off label to help prevent recurrent calcium-containing kidney stones in select patients.
Common indications for Aquazide in the USA include:
- Hypertension (primary high blood pressure) as monotherapy or in combination with other agents (ACE inhibitors, ARBs, calcium channel blockers, beta blockers)
- Edema related to congestive heart failure
- Edema due to liver cirrhosis or corticosteroid/estrogen therapy
- Edema associated with certain kidney disorders, including nephrotic syndrome
- Off-label: prevention of recurrent calcium nephrolithiasis (in carefully selected patients under clinician supervision)
Because thiazides can lower potassium and sodium levels, your clinician may recommend periodic lab monitoring and advise on diet, hydration, and, in some cases, potassium supplementation or use of a potassium-sparing agent. Modern U.S. guidelines recognize thiazides as a recommended first-line option for uncomplicated hypertension, with many clinicians preferring low starting doses to maximize benefit and minimize side effects.
Aquazide for high blood pressure (hypertension)
For adults with primary hypertension, Aquazide is typically started at a low dose and titrated based on your blood pressure response and tolerability. Many adults begin with 12.5 mg to 25 mg once daily. Providers may adjust the dose after several weeks if target blood pressure has not been achieved. Maximum daily doses above 50 mg seldom improve blood pressure further and are associated with a higher risk of metabolic side effects (e.g., low potassium, changes in blood glucose or uric acid).
Thiazide diuretics like hydrochlorothiazide often pair well with other first-line antihypertensives. Combination therapy can improve outcomes and reduce pill burden. If your clinician prescribes a fixed-dose combination (for example, with an ACE inhibitor or ARB), be sure to follow the product-specific dosing and monitoring instructions.
Lifestyle measures—such as a heart-healthy eating plan (DASH), reducing sodium intake, maintaining a healthy body weight, limiting alcohol, regular physical activity, and smoking cessation—amplify the blood pressure benefits of Aquazide and reduce long-term cardiovascular risk.
Aquazide for edema (fluid retention)
Edema occurs when excess fluid accumulates in tissues, leading to swelling, commonly in the legs, ankles, or feet. In conditions like congestive heart failure, cirrhosis, or certain kidney problems, Aquazide can assist by promoting diuresis—helping your body shed salt and water. Dosing for edema is individualized and may differ from hypertension dosing. Some patients require higher doses or a different dosing schedule (such as 25–100 mg daily, single or divided) based on response and clinical goals.
In moderate-to-severe volume overload or in patients with reduced kidney function, a loop diuretic (e.g., furosemide) may be used instead of—or in combination with—a thiazide. Your clinician will determine the most appropriate diuretic strategy, monitor your electrolytes and kidney function, and adjust therapy as needed.
Because diuretics increase urination, many patients find it most convenient to take Aquazide in the morning. If a second daily dose is prescribed, take it in the early afternoon to minimize nighttime bathroom trips.
Mechanism of action
Aquazide acts primarily in the distal convoluted tubule by inhibiting the sodium-chloride symporter. This inhibition decreases sodium and chloride reabsorption, increasing urinary excretion of sodium, chloride, and water, with associated excretion of potassium and hydrogen ions. The initial blood pressure reduction is related to decreased plasma volume; longer-term benefits likely involve a sustained reduction in peripheral vascular resistance. Onset of diuresis typically occurs within 2 hours, with peak effects around 4 hours and duration of action of 6–12 hours.
Safety overview
Hydrochlorothiazide has a long track record in U.S. clinical practice. While generally well-tolerated, it can cause electrolyte changes (low potassium, low sodium, low magnesium), increased uric acid (gout flares), mild increases in blood glucose and cholesterol in some patients, and photosensitivity. These effects are more likely at higher doses and in susceptible individuals (e.g., older adults, those with chronic kidney disease, or patients on interacting medications). Routine monitoring and individualized dosing help mitigate risk.
Dosage guidance for adults
Your exact dose should be determined by your prescriber. The following ranges reflect common U.S. practice:
- Hypertension: Start 12.5 mg to 25 mg once daily. If needed, titrate after several weeks. Doses above 50 mg/day generally provide limited additional blood pressure lowering and greater side-effect risk.
- Edema: 25–100 mg daily (single or divided), depending on response. In certain cases, intermittent dosing may be used.
- Older adults: Consider starting at the lower end of the range with closer monitoring due to an increased risk of electrolyte disturbances and orthostatic hypotension.
- Kidney function: Thiazides are less effective when estimated GFR is markedly reduced (e.g., <30 mL/min/1.73 m²). Your clinician may prefer a loop diuretic in that setting.
Take Aquazide in the morning with water. You can take it with or without food. If your clinician instructs a second dose, take it in the early afternoon. Try to take your dose at the same time each day. Do not change your dose or stop your medication without consulting your healthcare provider.
Titration and follow-up
After starting or adjusting Aquazide, your clinician may check your blood pressure, kidney function (serum creatinine), and electrolytes (especially potassium and sodium) within a few weeks. If levels are stable and your blood pressure is at goal, routine monitoring may be spaced out. Call your clinician if you develop symptoms such as dizziness, fainting, unusual fatigue, muscle cramps or weakness, persistent thirst, confusion, or significantly reduced urination.
Contraindications and precautions
Do not use Aquazide if you have:
- Anuria (inability to produce urine)
- Known hypersensitivity to hydrochlorothiazide or any component of the formulation
- A history of severe allergic reactions to sulfonamide-derived drugs (consult your clinician; cross-reactivity is uncommon but caution is advised)
Use caution and discuss with your clinician if you have or have had:
- Chronic kidney disease or reduced kidney function
- Liver disease (thiazides may precipitate hepatic coma in severe cirrhosis; careful monitoring is required)
- Gout or elevated uric acid
- Diabetes or prediabetes
- Electrolyte imbalances (low sodium, low potassium, low magnesium)
- Systemic lupus erythematosus (thiazides can exacerbate lupus in rare cases)
- Photosensitivity reactions to medications
Common side effects of Aquazide
Like all medications, Aquazide can cause side effects, though many are mild and manageable. Not everyone experiences them. Report any concerning symptoms to your healthcare provider promptly.
Potential side effects include:
- Dizziness or lightheadedness (especially when standing up suddenly)
- Headache or fatigue
- Increased urination
- Electrolyte changes: low potassium, low sodium, low magnesium
- Increased uric acid (could trigger gout flares)
- Changes in blood sugar or lipids (usually modest)
- Skin rash or photosensitivity (increased sunburn risk)
- Muscle cramps or weakness
Seek immediate medical attention for signs of a serious reaction: severe rash or hives, swelling of the face/lips/tongue, troublesome breathing, severe dizziness/fainting, confusion, or severe dehydration.
Managing and reporting side effects
Staying hydrated (as advised), moderating dietary sodium, and following your clinician’s guidance on potassium can help reduce risk. If you experience adverse effects, contact your clinician or pharmacist. In the U.S., you can also report side effects to the FDA MedWatch program.
Drug interactions
Tell your clinician and pharmacist about all prescription and over-the-counter medicines, vitamins, and herbal supplements you take. Important interactions with hydrochlorothiazide include:
- Lithium: Thiazides can increase lithium levels and toxicity risk. Avoid or monitor closely.
- Dofetilide: Co-administration with hydrochlorothiazide can raise dofetilide levels and risk of serious heart rhythm problems; this combination is contraindicated.
- Digoxin: Diuretic-induced hypokalemia can increase digoxin toxicity. Monitor potassium and consider supplementation if needed.
- Other blood pressure medicines: Additive effects can lower blood pressure more. Monitoring and dose adjustments may be needed.
- NSAIDs (e.g., ibuprofen, naproxen): May reduce diuretic and antihypertensive effects and affect kidney function; use with caution.
- Antidiabetic agents (insulin or oral agents): Thiazides may blunt glucose control in some patients; monitor and adjust therapy if needed.
- Corticosteroids or ACTH: May worsen potassium loss.
- Bile acid sequestrants (cholestyramine/colestipol): Can decrease hydrochlorothiazide absorption; separate dosing times.
- Alcohol, barbiturates, benzodiazepines, and other CNS depressants: Additive risk of orthostatic hypotension or dizziness.
This list is not exhaustive. Maintain an up-to-date medication list and share it at each medical visit.
Pregnancy and breastfeeding
Hydrochlorothiazide crosses the placenta and is excreted in breast milk. Use during pregnancy is generally not recommended in the United States unless clearly needed, because thiazides may reduce maternal plasma volume and can affect fetal/neonatal electrolyte balance and platelet counts. For breastfeeding, low doses may be compatible in some cases, but diuretics may reduce milk production—discuss risks and benefits with your clinician before use.
Practical pharmacist tips for Aquazide
Take Aquazide in the morning with a glass of water. Rise slowly from sitting or lying positions to reduce dizziness. If you’re prescribed a second daily dose, take it in the early afternoon to avoid nighttime urination. Protect your skin from sun exposure and consider using sunscreen due to photosensitivity risk. Keep your follow-up appointments for blood pressure checks and lab monitoring.
Ask your clinician about dietary potassium. Many patients can maintain levels through a balanced diet (e.g., fruits and vegetables), but others may require a supplement or a potassium-sparing strategy. Do not start potassium supplements without clinical guidance.
If you’re also taking an ACE inhibitor or ARB, your clinician will monitor your kidney function and potassium levels, particularly after dose changes. Report persistent muscle cramps, fatigue, or palpitations, which may signal an electrolyte imbalance.
Safety precautions
Do not take Aquazide if you are unable to urinate (anuria) or if you are allergic to hydrochlorothiazide. Use caution with alcohol—it can amplify dizziness or low blood pressure. If you develop severe nausea, vomiting, or diarrhea, contact your clinician, as excessive fluid loss can worsen side effects. Inform all your healthcare providers that you take hydrochlorothiazide, especially before surgeries or procedures.
Signs of electrolyte imbalance
Call your clinician if you notice symptoms that may indicate low sodium or potassium, such as confusion, severe fatigue, unusual muscle weakness, cramps, irregular heartbeat, or increased thirst. Routine blood tests help detect these issues early.
Special populations and monitoring
Thiazide diuretics require thoughtful use in specific populations:
- Older adults: More susceptible to electrolyte changes and orthostatic hypotension. Start low and go slow with dosing and monitor closely.
- Kidney impairment: Efficacy decreases as kidney function declines. Your clinician may choose alternative diuretics or combinations and will monitor kidney function and electrolytes.
- Liver disease: Use carefully; monitor for electrolyte disturbances that can precipitate hepatic encephalopathy.
- Gout: Hydrochlorothiazide can increase uric acid and trigger flares; discuss preventive strategies if you have a history of gout.
- Diabetes: Small increases in blood glucose may occur; monitor and adjust antidiabetic therapy as needed.
Typical monitoring includes blood pressure, serum electrolytes (potassium, sodium, magnesium), kidney function (serum creatinine/eGFR), and, in some cases, uric acid and glucose. Your clinician will tailor the frequency of checks to your individual risk profile and response to therapy.
Kidney stones and calcium balance
Because hydrochlorothiazide reduces urinary calcium excretion, it may be considered off label to help prevent recurrent calcium-containing kidney stones in select patients. If prescribed for this purpose, clinicians often aim for a lower, steady dose with close electrolyte monitoring and dietary guidance (adequate fluid intake, moderation of sodium, and appropriate dietary calcium). Do not self-treat kidney stones with Aquazide—use only under specialist supervision.
Storage, missed dose, and overdose
Store Aquazide tablets at room temperature, away from moisture and heat, and out of reach of children and pets. If you miss a dose, take it when you remember on the same day. If it’s close to your next dose, skip the missed dose—do not double up. In case of overdose (symptoms may include profound dizziness, fainting, or severe dehydration), seek emergency medical attention or call your local poison control center in the USA at 1-800-222-1222.
Cost-saving tips for U.S. patients
If you are paying cash, ask your pharmacy about generic pricing and 90-day fills. Many large chains and independent pharmacies offer competitive savings programs on widely used generics like hydrochlorothiazide. Manufacturer coupons typically do not apply to generics, but discount cards may help lower your cost. If your prescriber approves, switching to a fixed-dose combination pill can reduce copays and simplify your regimen.
Recommendations from our specialists
Hypertension remains one of the most modifiable cardiovascular risk factors in the United States. Thiazide diuretics such as Aquazide have a long history of helping patients reach blood pressure goals safely and effectively when used and monitored correctly. Our clinical partners recommend combining medication with sustainable lifestyle measures—including sodium reduction, weight management, and consistent physical activity—for the best long-term outcomes. If you are starting Aquazide, arrange a follow-up plan to review your blood pressure readings and lab results. Our U.S.-based pharmacy partners provide timely delivery, easy refills, and pharmacist support whenever you have questions.
Ready to take control of your blood pressure? Order Aquazide today
Get fast, discreet delivery from a U.S. pharmacy with access to licensed clinician review when needed. Manage hypertension and edema with a proven, guideline-supported medication.
- Prescription required in the USA — telehealth evaluation available for eligibility
- Fast, secure shipping throughout the United States, with tracking
- Authentic medication from licensed U.S. pharmacy partners
- Affordable options across 12.5 mg, 25 mg, and 50 mg strengths
- Pharmacist support to help with dosing, side effects, and refills
Join thousands of U.S. patients who rely on thiazide therapy as part of their blood pressure management. When prescribed appropriately and monitored regularly, Aquazide can be an effective, cost-conscious option for both hypertension and edema.
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